Alcohol-RelatedPancreatic Damage

نویسندگان

  • MINOTI V. APTE
  • S. WILSON
  • MARK A. KORSTEN
چکیده

abuse and pancreatic injury was reported as early as 1878 (Friedreich 1878). Alcoholic pancreatitis is a potentially fatal illness that may be short term (i.e., acute) or long term (i.e., chronic). The relationship between acute and chronic pancreatitis is complex. Symptoms shared by acute and chronic pancreatitis include disabling abdominal pain and interference with normal pancreatic functions. Although the prevalence of alcoholic pancreatitis in the population is unknown, clinicians usually agree that both acute and chronic alcoholic pancreatitis are responsible for a significant amount of illness and death in the United States. This article discusses the extent of the problem, clinical aspects, diagnosis, development (i.e., pathogenesis), and treatment of both acute and chronic alcohol-related pancreatitis. THE HEALTHY PANCREAS

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

​The Effects of two Weeks Exhaustive swimming and Curcumin Supplementation on Liver Damage Biomarkers Caused by Alcohol Consumption in Male Wistar Rats

Background: Curcumin is an active ingredient in turmeric, which is used as herbal medicine for the treatment of certain diseases. The aim of this study was to investigate the effects of two weeks of exhaustive swimming and supplementation of curcumin on alcohol induced liver damage biomarkers in male wistar rats. Materials and Methods: In this study, 32 male wistar rats were randomly selected ...

متن کامل

P 95: Result of Alcohol Excessive Drinking in the Brain and Varying Mental Health Side Effects

Alcohol directly affects astroglial cell function, including inflammation-related activity.  And it also affects microglial cell development and function in specific ways that interfere with microglial interactions with the immune system and with neurons. Neuroinflammatory processes might be involved in alcohol-induced brain damage. Alcohol use, misuse and getting used to it causes differe...

متن کامل

P-237: Chronic Alcoholism Induced Male Infertility :Impairment of Sperm Quality

Background: Prolonged alcohol abuse in men can cause testosterone deficiency and shrinkage of the testicles (testicular atrophy). This can lead to impotence, sterility and ‘feminisation’. When alcohol is broken down in the body, it may also interfere with normal sperm structure and movement. This study was designed to determine the effects of administration of alcohol on sperm quality, sperm ma...

متن کامل

p53 pathway determines the cellular response to alcohol-induced DNA damage in MCF-7 breast cancer cells

Alcohol consumption is associated with increased breast cancer risk; however, the underlying mechanisms that contribute to mammary tumor initiation and progression are unclear. Alcohol is known to induce oxidative stress and DNA damage; likewise, p53 is a critical modulator of the DNA repair pathway and ensures genomic integrity. p53 mutations are frequently detected in breast and other tumors....

متن کامل

Overview: how is alcohol metabolized by the body?

Alcohol is eliminated from the body by various metabolic mechanisms. The primary enzymes involved are aldehyde dehydrogenase (ALDH), alcohol dehydrogenase (ADH), cytochrome P450 (CYP2E1), and catalase. Variations in the genes for these enzymes have been found to influence alcohol consumption, alcohol-related tissue damage, and alcohol dependence. The consequences of alcohol metabolism include o...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2000